Regions
Asturias is made up of roughly three regions, each corresponding to an area bounded by rivers. While in no way reflected in official or scholarly sources, this is my rough mental map of Asturias. I find it to be a useful way to think of the various parts of the region, and I hope it can help you to learn a bit more about the variation or experiences within Asturias. It can also be used to decide where you would like to spend your time in Asturias, as each region has it's own unique rhythm and flavor.
Western Asturias
Made up of the comarcas of Eo-Navia and Narcea, this is the area between the Eo river on the border with Galicia and the lower reaches of the Nalón river and the Trubia river above that.
This is farming country, and very sparsely populated. It contains the only wine region in Asturias, the DOP Cangas. If you want a bucolic setting with wineries and stone houses with slate roofs, this is where you should go.
Central Valley
Comprised of the comarcas of Avilés, Gijón, Oviedo, Caudal and Nalón, it lies between the Trubia and Sella rivers.
This is the industrial heart of Asturias, and the most densely populated area. All of the cities of Asturias are located here, as well as the majority of the cider llagares. This is the bustling center, in more ways than one. If you are looking for festivals, walkable cities, and nightlife, this is your jam.
Eastern Asturias
Comprised entirely of the Oriente comarca, this is the are lying east of the river Sella, to the border with Cantabria.
This is cattle ranching Asturias, and the home of the world famous blue cheeses. It is also ground zero for active tourism in Asturias, with some of the best rock climbing and alpinism to be had in all of Spain. If you are looking for an international destination for outdoor pursuits, rugged landscapes, and "campervans welcome" signs, this is where you want to head.